https://www.selleckchem.com/pr....oducts/mi-773-sar405
Y376 is located in a linker between the PH and GAP domains and is invariant in GRAF3 homologues and a phosphomimetic E376GRAF3 variant exhibited elevated GAP activity. Collectively, these data provide strong support for the future identification of allosteric activators of GRAF3 for targeted anti-hypertensive therapies.Traditional guidance on ladder safety emphasizes training workers on the use of three points of contact. More recent guidance is to train workers to use three points of control. What is lacking is empirical infor
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