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Best Medication For ADHD The use of medication is an integral part of the majority of treatment plans for ADHD. But finding the best dosage and medication may take time. Be patient and open to communicating with your doctor. Stimulants are used to increase levels of brain chemicals which help regulate behavior. They come in short-acting and long-acting formulations. Short-acting medicines reach their peak within several hours and are typically taken 3-4 times a day. Long-acting medication lasts