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ADHD Medication Medication is usually a part of an ADHD therapy plan. The two most commonly used stimulant drugs are dextroamphetamine as well as methylphenidate. Each of these has many brand names and has a different chemical makeup. Stimulants stimulate brain chemicals that help transmit messages between neurons. These are usually the first medications healthcare providers consider for adults with ADHD. Stimulants Stimulants are the first medications most doctors prescribe to treat ADHD. They