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https://ml210inhibitor.com/pop....ulation-plan-househo
Taking into consideration the cellular heterogeneity and also the relationship between dropout price and anticipated expression amount, we provide a cell sub-population based bounded low-rank (PBLR) approach to impute the dropouts of scRNA-seq data. Through application to both simulated and genuine scRNA-seq datasets, PBLR is shown to be effective in recovering dropout events, and it may considerably increase the low-dimensional representation plus the data recovery of gene‒gene interactions masked by dropo