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Finding the Best ADHD Medication For Adults Stimulants such as methylphenidate or amphetamine, (Vyvanse) are quick to balance brain chemicals. These medications can cause loss of appetite, sleep problems, weight changes and the appearance of tics in some people. Atomoxetine, in conjunction with other antidepressants like bupropion, are nonstimulants that slow down the treatment of ADHD symptoms. They increase a chemical in the brain that is known as norepinephrine. This helps improve conc