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CUF ended up being no difference in intraoperative purple cell transfusions in comparison to controls (letter = 2); otherwise 3.09; 95% CI 0.26-36.59; p = 0.37; p for heterogeneity = 0.94, I2 = 0%. Review of the included observational researches revealed an association between bigger amounts (2.2 L in a 70 kg client) of CUF and chance of severe renal injury (AKI).Conclusion The results of this systematic review and meta-analysis declare that MUF is involvi