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Sixty-one men and 87 women participated. Average age, 46 ± 12 years; Expanded Disability Status Scale, 3 (1-6.5); symptom duration, 10.8 ± 9.4 years. The cohort showed significant worsening in all standing conditions (P less then .001), sensation (P = .0223) and strength (P = .001); but more stability in walking with only velocity (P less then .0337) significantly declining. For each sex, postural sway declines significantly in all conditions (P less then .01) except for eyes closed feet together for women. Strength declines significantly by sex for h