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ach outperform all leading unsupervised methods discussed in terms of specificity and accuracy. In addition, it outperforms most of the state-of-the-art supervised methods without the computational cost associated with these algorithms. Detailed visual analysis has shown that a more precise segmentation of thin vessels was possible with the proposed approach when compared with other procedures.Functional magnetic resonance imaging (fMRI) is a non-invasive method that helps to analyze brain function based on BOLD signal fluctuations. Fun