https://www.selleckchem.com/pr....oducts/z-4-hydroxyta
Targeting proteolytic neoepitopes could provide an orthogonal "AND" gate for improving the therapeutic index.Osteocalcin is a hormone produced in bones by osteoblasts during bone formation. Numerous studies have demonstrated that adrenal gland-derived glucocorticoids inhibit osteocalcin production, which can ultimately cause deleterious bones loss. This loss establishes a unidirectional endocrine relationship between the adrenal glands and bone, however, whether osteocalcin reciprocally regulates glucocorticoid secretion re