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• High oncologic-risk patient recognition and close followup are crucial. • Recurrences diagnosed inside the first 2 years after OLT could be categorized as early-onset and therefore are involving bad prognosis. • Surgical resection must be the first curative attempt when it's theoretically possible. • TACE in patients that have encountered OLT seems to be secure and efficient. • Sorafenib can be utilized as systemic treatment in situations with multi-organ recurrence; newer th