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Treatment satisfaction in patients with atopic dermatitis (AD) has been investigated in several studies, but the desire for alternative treatment options is unclear and has not been previously evaluated. We conducted a cross-sectional, web-based survey aimed at evaluating the desire for alternative treatment options in adults with AD from a patient registry in Japan. Main eligibility criteria were adults aged ≥ 18years with AD who were receiving treatment with topical corticosteroids (TCS) and not systemic therapy. Questionnaires includ