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This review will focus on whole-body functional imaging applied to lung cancer disease and patient management. Lung cancer needs to be avoided… (but if not well succeeded), suspected, screened, histologically confirmed, anatomically inventoried, prognostically staged, molecularly characterized, genetically studied and finally, therapeutically managed. Functional imaging using 18F-fluoro-deoxy-glucose (FDG) is a non-invasive method that is widely used in oncologic disease, mainly for clinical staging and re-staging, with impact on therapy p