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In a case-control study, we gauge the associations between cyclooxygenase-2 (COX2), epidermal growth factor (EGF), EGF receptor (EGFR), and tumefaction suppressor P53 SNPs regarding the danger of LSCC development into the Chilean population. A complete of 85 LSCC customers and 95 healthy volunteers were recruited. SNPs genotype had been reviewed from genomic DNA by Polymerase Chain response (PCR)-Restriction Fragment Length Polymorphism (RFLP) and associations