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BACKGROUND Heart failure (HF) is a hypercatabolic state that promotes branched-chain amino acid (BCAA) catabolic activity into the heart and skeletal muscle tissue and reduces protein synthesis within the liver. Consequently, plasma free fragrant proteins (AAAs) are increased. We investigated the prognostic worth of the BCAA/AAA proportion (Fischer's proportion, FR) in customers with HF. METHODS We enrolled 157 successive clients hospitalized for worsening HF (81 men, 76 women; mean ±