https://www.selleckchem.com/pr....oducts/picrotoxin.ht
Analysis of 47 antral and 39 duodenal biospecimens revealed 5 candidate genes significantly associated with pain burden antral EDN1, PTGES3 and duodenal HTR1A, P2Y1, SCN3A (p0.01). Subsequent stringent statistical analysis comparing those with significant pain versus no pain revealed antral PTGES3 and duodenal SCN3A were the highest priority candidate genes (p0.001). Pain burden in pediatric FD may be linked to antral EDN1, PTGES3 and duodenal HTR1A, P2Y1, SCN3A differential expression. These genes are known to be involved in