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However, no association was found with the and polymorphisms. Moreover, the pooled results of subgroup analysis by ethnicity suggested significant association between , and polymorphisms and T2D in some subgroups. Meta-regression analyses indicated that none of the publication year, ethnicity, and genotyping method were the source of heterogenicity in all four polymorphisms. This meta-analysis suggested a significant association between gene , and (heterozygote model) polymorphisms and T2D susceptibility in overall population