https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Despite decades of research on pathophysiology of myocardial stunning, protein changes and/or phosphorylation status underlying alterations in cardiac function/structure remain inadequately understood. Here, we utilized comprehensive and quantitative proteomic and phosphoproteomic approaches to explore molecular mechanisms of myocardial stunning in swine. The closed-chest swine (n=5) were subjected to a 10-minute LAD occlusion producing regional myocardial stunning. Tissues from the ischemic LAD region and a remote non-isch