Causes of Truck Crash Accidents If a truck crashes, the driver may be the cause, but there are other factors that could cause an accident. Driver fatigue, impaired driving and trucks carrying dangerous cargo are some of the most common causes of truck accidents. Companies that produce such equipment may also be held liable for injuries. In any event medical attention must be sought as soon as is possible, and you should see your primary care physician if you have any injuries. Keep a record of the crash and share information with the other pa