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Main regional individual astrocytes had been analyzed for iP legislation and function by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), Western blot, OxyBlot, and reactive oxygen species and caspase activity recognition assays. Following immunization with myelin oligodendrocyte glycoprotein (MOG)35-55, the role of IFNγ signaling additionally the iP during chronronic EAE associated with minimal iP expression, enhanced lesion size and oxidative tension,
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