https://www.selleckchem.com/pr....oducts/piperlongumin
e of GLUT-1/3 inhibitors. These markers were significantly decreased following C+P administration with the induced hypothermia, while C+P administration with temperature control at 37°C induced lesser protection after ischemia stroke. In the OGD/reoxygenation model, C+P treatment increased cell viability and diminished protein levels of HIF-1α, GLUT-1, GLUT-3, PFK-1, LDH, and gp91 . However, in OGD with HIF-1α overexpression, C+P was unable to effectively reduce the upregulated GLUT-1, GLUT-3, and LDH. In normal conditions, C+P r