https://www.selleckchem.com/pr....oducts/dl-ap5-2-apv.
In PMN-Arf6 cKO mice, the recruitment of PMNs into the dorsal air pouch injected with LPS or the chemoattractant fMLP was significantly diminished. Impaired cell migration correlated with reduced cell surface expression of CD11a and CD11b in Arf6 cKO PMNs. Our results highlight that Arf6 regulates the activity and possibly the recycling of PMN integrins, and this compromises PMN migration to inflammatory sites. Copyright © 2020 Jouda Gamara et al.L-arginine (Arg) is a semiessential amino acid with several physiological functions. N