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ADHD Medication Side Effects If your doctor prescribes ADHD medicine, you or your child may experience adverse effects. It may take some trial and error to determine the best medication and dose for you. Stimulants are among the most popular drugs used to treat ADHD. They boost brain chemicals, which affect concentration and attention. Doctors also prescribe Guanfacine (brand names Tenex and Intuniv) and clonidine (Catapres) to reduce tics and impulsive behavior in people suffering from