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411; P less then 0.001], stromal component (low vs. high HR, 1.876; 95% CI, 1.227-2.870; P = 0.004), tumor grade (G3 vs. G1/2 HR, 2.124; 95% CI, 1.419-3.179; P less then 0.001), and perineural invasion (with vs. without HR, 2.147; 95% CI, 1.187-3.883; P = 0.011) were independent prognostic factors in the developing cohort. Stromal component categories could classify patients into subgroups within TNM stages I, II, and III based on over survival. All results were validated in the validation cohort. The weighted kappa value for categorical a