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Only a few techniques have been developed to track molecular transport at the osteochondral interface, and there appear opportunities for development in this field. This review will describe current knowledge of the molecular interactions and transport in the osteochondral interface and discuss the potential of using contrast agents for investigating molecular transport and structural changes of the joint.[This corrects the article DOI 10.3389/fcell.2020.00540.].Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of