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rametinib. This needs clinical assessment. Our results demonstrate the role of insulin in reducing the efficacy of vemurafenib and trametinib. This needs clinical assessment. Early detection of breast cancer saves lives. Existing detecting techniques are invasive. Electrical bioimpedance is a noninvasive technique and has a high diagnostic potential. An impedance value different from the normal can predict a physiological abnormality. The idea is to use a designed bioimpedance device to early detect breast cancer. A low-frequency current (