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Overall, 31.1% of patients on antibiotics on admission to the ICU were positive for CRGs compared to 16.5% not on antibiotic therapy (P 0.001). CRG detection was also more common among patients aged 65 years (P= 0.027) and increased with hospital length of stay (P= 0.025). The rate of CRGs detected in hospitalized patients in GCC countries varied considerably. Prior antibiotic exposure, increasing age, and prolonged length of stay were associated with CRG detection. The rate of CRGs detected in hospitalized patients in GCC count