https://hdac-signaling.com/ind....ex.php/basic-safety-
Most frequently, beginning and very early childhood tend to be regular. Untreated individuals have slowing of linear growth at age someone to three years, followed closely by development of spasticity, plateauing of cognitive development, and subsequent loss of developmental milestones. If untreated, arginase deficiency often progresses to severe spasticity, loss of ambulation, full loss of bowel and bladder control, and extreme intellectual impairment. Seizures are common and