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PRODUCTS AND METHODS The cytotoxic impacts had been determined using MTT assay. Apoptosis had been quantitated by annexin V-FITC/PI staining. Caspases tasks were calculated making use of specific substrates and colorimetric evaluation. The necessary protein expressions had been based on Western blot analysis. Reactive air species (ROS) generation, mitochondrial transmembrane potential, and calcium ion levels were assessed by specific fluorescence probes and circulation cytometry. The
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