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Non Stimulant ADHD Medication Stimulants increase dopamine and neurotransmitters norepinephrine and norepine which help with motivation and alertness, concentration and effort. They also help increase focus and concentration. Non stimulant ADHD medications are usually prescribed when stimulants fail to work, cause intolerable side effects or a person is unable to use them due to medical reasons. Clonidine (Kapvay), and guanfacine (Intuniv) are two examples. Stimulants Stimulants are a