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Area underneath the curve (AUC) associated with the models and pooled observers had been contrasted using the DeLong test. The optimal pre-, post-, and delta-radiomic models yielded an AUC of 0.717 (95% CI 0.639-0.795), 0.805 (95%CWe 0.736-0.874), and 0.724 (95%Cwe 0.648-0.80, correspondingly. The radiomic nomogram centered on pre-nCRT cN stage, pre-nCRT radscore, and post-nCRT radscore realized an AUC of 0.852 (95%Cwe 0.774-0.93, that has been higher than the solitary radiomic mod