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ADHD Medication UK For Adults The first medication prescribed is typically an stimulant, such as methylphenidate. It increases the activity of parts of the brain which regulate attention and behavior. Long-acting formulas are also available and are the preferred medication for adults with ADHD. are slowly absorbed into the bloodstream, avoiding 'crash" that can occur after short-acting medication wears off. Stimulants Stimulants, which boost levels