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A p value of 0.05 was considered significant for all analyses. The frequency of RLS among cirrhotic patients was 38.4%. More than half (54.5%) of the patients had severe RLS. Viral related (hepatitis C and hepatitis were the most common cause of cirrhosis of liver (57.8% and 30.8%). Significant difference was found between patients with RLS and without RLS in terms of age (p=0.003), gender (p=0.005), hemoglobin (p=0.0, and serum albumin (p=0.01). No significant association was found between RLS severity score and MELD Score