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HCV infection seems to impair HBV vaccine reaction, with cirrhosis being the actual only real recognizable risk factor for hypo-responsiveness among studied clinical and virus-related variables.HCV infection appears to impair HBV vaccine reaction, with cirrhosis becoming truly the only identifiable risk factor for hypo-responsiveness among studied clinical and virus-related variables.Tumor antigen-primed CD8 T cells differentiate into effector T cells that kill tumefaction cells rapidly, wherea