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All rights reserved.INTRODUCTION Lupus nephritis (LN) is a common problem of systemic lupus erythematosus (SLE), which is a chronic autoimmune disease. But, the detailed mechanisms fundamental this disorder have actually remained unclear. Alpha2-antiplasmin (α2AP) is well known to perform different functions, such plasmin inhibition and cytokine manufacturing, also to be connected with immune and inflammatory reactions. TECHNIQUES We investigated the roles o