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Furthermore, MAT enhanced PDCD4 phrase by up-regulating LINC00472. Besides, we discovered MAT elevated PTEN but restrained PI3K/AKT proteins. Eventually, cyst amount and weight had been declined by pad in vivo via up-regulating LINC00472. Conclusion MAT restrained mobile growth and metastasis but presented PDCD4 appearance by up-regulating LINC00472 via restraining PTEN/PI3K/AKT pathway in BC. © 2020 Li et al.Background As a key subtype of non-coding RNAs, circular RNA (