https://www.selleckchem.com/pr....oducts/Mubritinib-TA
An efficient copper-catalyzed cyclization of N-propargyl ynamides with borane adducts through B-H bond insertion has been developed. A series of valuable organoboron compounds are constructed in generally good yields with a wide substrate scope and good functional group tolerance under mild reaction conditions. Importantly, this protocol via vinyl cation intermediates constitutes a novel way of B-H bond insertion.Nodal monoloop, enjoying the cleanest scenario with a single loop, is recognized as the basic building block of in