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To assess the effect of contralateral dependent position on procedures and complications of percutaneous computed tomography (CT)-guided core needle biopsy (PCT-CN for small (≤ 20mm) lung lesions adjacent to the pericardium. Retrospective view was performed to identify patients with small (≤ 20mm) lung lesions located within 10mm of the pericardium and who underwent PCT-CNB in the standard supine or prone position (n = 66) or in contralateral dependent position ( n=35) between March 2010 and January 2020. In 35 patients, CT images in