https://www.selleckchem.com/ph....armacological_epigen
The extension of the metastatic lymph nodes through the capsule to the adipose tissue in perinodal or extra-nodal defines the extra-nodal extension (ENE). ENE represents an important prognostic factor in multiple cancers, which is considered as a prognostic parameter in different tumor-node-metastasis (TNM) classifications.
<p> Introduction Colorectal cancer (CRC) is ranked third in order of frequency, after successively lung and breast cancer. Lymph node metastasis has been validated as a significant negative prognostic fa