https://www.selleckchem.com/pr....oducts/epz004777.htm
It has been shown that periodontitis, can be modified by systemic changes, including behavioral factors, such as diet. Caloric restriction is one of the dietary therapeutic strategies indicated for obesity. It is associated with several benefits, among them, modulation of the inflammatory response. The aim of this study was to verify whether caloric restriction in obese rats changes the progression of experimental ligature-induced periodontitis. Forty-eight Wistar rats were used for 24weeks and initially fed with cafeteria diet during