https://ravoxertinibinhibitor.....com/possible-suppres
OUTCOMES Pemetrexed resistant cells revealed significantly increased expression of HH signaling genes (GLI1, GLI2, GLI3, PTCH1, SHH). Encouraging these results, pemetrexed resistant cells treated with the HH inhibitor Gant61 showed decreased proliferation compared to naïve cells. SUMMARY HH path may play an important role in mediating pemetrexed resistance in NSCLC cells. Blocking the HH pathway could be a potential choice to conquer this opposition. BACKGROUND/AIM Although
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