https://www.selleckchem.com/pr....oducts/pirfenidone.h
18, C.I.95% 2.20-17.40; p=0.001) but not in those who were downstaged for the increase in age cut-off (HR 2.80, C.I.95% 0.86-9.19; p=0.09). In conclusion, TNM 8th edition did not show reliability in predicting aggressiveness of DTC. In fact, the downstaging of DTC patients especially when performed due to changes in tumour classification may overlook patients predisposed to structural recurrence, potentially causing uncertainty in the therapeutic decision-making at the time of disease's diagnosis.Metastatic duodenopancreatic neuro-e
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