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On the left side of the inflection point, the OR was 0.996 (OR 0.996, 95%CI 0.994-0.998, 0.001). On the right side of the inflection point, the OR was 1.011 (OR 1.011, 95%CI 1.001-1.021, = 0.029). A U-shaped association between platelet count and in-hospital mortality was found in the patients with COVID-19. The optimal of platelet count associated with the lowest risk of in-hospital mortality was around 370 × 10 /L. A U-shaped association between platelet count and in-hospital mortality was found in the patients with COVID-19. The o
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