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Besides, grafted PNIPAM chains exhibited a higher glass transition temperature. The grafted keratin particles displayed enhanced hydrophilicity. Keratin-g-PNIPAMs exhibit a lower LCST comparing to homopolymer and the flocculation in hot water behavior could be controlled by regulating graft rate. V.As a highly efficient and environmentally friendly biocatalyst, immobilized lipase has received incredible interest among the biotechnology community for the production of biodiesel. Nanomaterials possess high enzyme loading, low mass transfer