https://www.selleckchem.com/products/ZLN005.html
Curcumin, a major bioactive curcuminoid derived from the rhizome of , is known to have anticancer potential and is still under investigation. In this study, we investigated the cytotoxic mechanism(s) of curcumin against acidity-tolerant prostate cancer PC-3AcT cells in lactic acid-containing medium. Using 2D-monolyer and 3D spheroid culture models, MTT assay, annexin V-PE binding assay, flow cytometric analysis, measurement of ATP content, and Western blot analysis were used for this study. At nontoxic concentrations in normal prostate e
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