https://www.selleckchem.com/pr....oducts/Sunitinib-Mal
003) and driven primarily by 'hypofunctional' TLR responses (p values 0.045, 0.010 0.018 for TLR4-mediated IL-10, IL-1β TNF-α respectively; 0.018 0.015 for TLR1-2 -mediated IL-10 IL-1β). Hierarchical clustering generated three distinct clusters of patients and a fourth group of 'unclustered' individuals. No relationship was observed between the observed immune clusters and the clinical disease phenotype. CONCLUSIONS Although a clinically useful outcome was not observed through hierarchical clust