https://www.selleckchem.com/pr....oducts/sulbactam-piv
Ligand Q1 could adopt an appropriate pose at terminal G-quartets of ASC20 through multiple interactions including π-π stacking between aromatic rings; this led to strong fluorescence enhancement. In addition, a co-staining image showed that Q1 is mainly distributed in the cytoplasm. Accordingly, this work provides insights for the development of ligands that selectively targeting a specific G4 DNA structure.Mammalian body temperature oscillates with the time of the day and is altered in diverse pathological conditions. We rece