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Best Medication For ADHD The use of medication is an integral part of many treatment strategies for ADHD. However, finding the right medication and dose can take time. Be patient and open to communicating with your GP. Stimulants increase the amount of the chemicals that regulate behavior in the brain. They are available in short-acting and long-acting formulations. Short-acting medications peak within several hours and must be taken 2-3 times a day. Long-acting medications last 8-12 hours and are typically taken once a day. Stimulant