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ADHD Medication Medication is often an integral part of an ADHD treatment strategy. The two most popular stimulant drugs are dextroamphetamine as well as the methylphenidate. Each of these has many brands and each has a different chemical makeup. Stimulants increase the levels of brain chemicals that aid in transmit messages between neurons. These are usually the first drugs doctors try for adults with ADHD. Stimulants Stimulants are the primary medication that doctors prescribe for ADHD. work by increasing levels of a certain chemical in