https://www.selleckchem.com/products/GDC-0941.html
Voriconazole primary metabolism is catalysed by CYP2C19. A large variability of trough concentrations in patients with invasive fungal infection treated with voriconazole has been observed in clinical practice. It remains controversial whether the CYP2C19 polymorphisms are responsible for voriconazole metabolism in the individual variation. The primary aim of this study was to assess the effect of CYP2C19 polymorphisms on voriconazole trough concentrations. Following a systematic literature review, we performed a meta-analysis for mean