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ADHD Medications - Stimulant Or Non Stimulant? For many stimulant medications are the first choice for treating ADHD. Certain people experience negative side effects or they do not perform as well. Some doctors prescribe stimulants in addition to non-stimulant ADHD medications. These include medications to treat high blood pressure, such as clonidine or Guanfacine (Tenex). These include other medicines that promote the state of being awake. Benefits Stimulants are among the first drugs doctors usually prescribe to treat ADHD. They help improve the b